However, it has been realized that a similar reaction would occur with ketones and reactive carbonyl compounds with available α-hydrogens (the need for these α-hydrogens will be …

The cross Aldol condensation of isobutyraldehyde and formaldehyde performed using a basic phase transfer catalyst at 20 °C showed 100% conversion of isobutyraldehyde with 100% selectivity of the product hydroxypivaldehyde (including 2–5% of NPG formed). Chemicals used, procedure, author comments, data and references for: Aldol condensation of benzaldehyde and acetone. Crossed Aldol Condensations Using Weak Bases: Crossed aldol reactions are possible with weak bases such as hydroxide or an alkoxide when one carbonyl reactant does not have an a hydrogen . Aldol condensation occurs in aldehydes having α-hydrogen with a dilute base to give β-hydroxy aldehydes called aldols.

Figure 1: Aldol condensation of benzaldehyde and acetone to dibenzalacetone To avoid the use of cooling and controlled reagent addition, FutureChemistry has translated this reaction from a batch process to a continuous flow process. The enzymes benzaldehyde lyase and benzoyl formate decarboxylase both catalyze benzoin condensations with enantiopure products. The mechanisms for acid catalyzed aldol condensation and base catalyzed aldol condensation is significantly different. Another way to control the stereochemistry of benzaldehyde condensations is through enzymatic methods. If the condensation reaction occurs between two different carbonyl compounds it is … This page deals with the base catalyzed reaction of aldol condensation and its mechanism.

This reaction is most commonly known as aldol condensation. Which of the following compounds would undergo aldol condensation, which the Cannizzaro reaction and which neither? Aldol condensation reaction can be either acid catalyzed or base catalyzed. This reaction was thought to occur only with aldehydes. This condensation is often followed by spontaneous dehydration due to β-elimination to produce an α,β-unsaturated aldehyde or α,β-unsaturated ketone. Write the structures of the expected products of aldol condensation and Cannizzaro reaction.

The enzymes produced R enantiomers with an enantiomeric excess of greater than 99%.8 Another modification of the aldol condensation is the Claisen condensation…

(i) Methanal (ii) 2-Methylpentanal (iii) Benzaldehyde (iv) Benzophenone (v) Cyclohexanone (vi) 1-Phenylpropanone (vii) Phenylacetaldehyde